Hi ndamico,
ISAPI is faster than FastCGI. FastCGI is faster than CGI (20x for /helloworld.php on Windows).
CGI and FastCGI have the same reliability when running PHP. For many sites, running PHP as an ISAPI is unreliable (e.g. some extensions aren't thread safe).
If you are experiencing excellent reliability with ISAPI then stick with it. (try "logparser "SELECT sc-status,COUNT(*) FROM u_ex071010.log GROUP BY sc-status" to get an idea of your current reliability, 500=bad, 200=good)
Cheerz,
Rick.